| 產(chǎn)品名稱 |
Escherichia coli (Migula) Castellani and Chalmers |
| 商品貨號(hào) |
B161489 |
| Reports |
Upon your purchase of this product, you will receive a report containing MIC values, a susceptibility profile, and the DNA sequence information for predicted annotated antibiotic resistance genes and 16S rRNA genes. This report will be provided in multiple formats (.pdf, .txt, .xls, .zip). |
| Deposited As |
Escherichia coli |
| Verified By |
Whole-genome Sequencing |
| Classification |
Enterobacteriaceae, Escherichia |
| Strain Designations |
1136922 |
| Application |
Drug discovery and development
Development of molecular-based detection assays
Development of updated sterility protocols |
| Isolation |
Urine |
| Isolation Date |
2014 |
| Geographic Source |
Israel |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format |
frozen |
| Storage Conditions |
-80°C or colder |
| Preceptrol® |
no |
| Annotated Genes |
AAC(3)-IIa
AAC(6')-Ib-cr
acrA
acrB
acrD
acrE
acrF
APH(3'')-Ib
APH(6)-Id
baeR
catB3
CMY-2
CMY-47
emrB
KPC-2
macA
macB
marA
mdtB
mdtC
mdtF
msbA
OXA-1
qnrB20
TEM-1
tet(G)
tolC
|
| Type Strain |
no |
| MIC Range |
Susceptible
Amikacin: ≤16 µg/mL
Fosfomycin: ≤64 µg/mL
Intermediate
Doripenem: 2 µg/mL
Imipenem: 2 µg/mL
Resistant
Amoxicillin-clavulanate: ≥32/16 µg/mL
Aztreonam: ≥16 µg/mL
Cefepime: ≥16 µg/mL
Ceftazidime: ≥16 µg/mL
Ceftriaxone: ≥4 µg/mL
Ciprofloxacin: ≥4 µg/mL
Levofloxacin: ≥8 µg/mL
Meropenem: ≥4 µg/mL
Piperacillin-tazobactam: ≥128/4 µg/mL
Tetracycline: ≥16 µg/mL
Trimethoprim-sulfamethoxazole: ≥4/76 µg/mL
|
| Comments |
This strain is part of the Global Priority Superbugs collection. It is an extensively characterized antimicrobial-resistant clinical isolate with validated genotypic and phenotypic activity against a variety of drug classes. This strain is provided with geographic source information; an NGS-assembled whole genome sequence, including annotated antibiotic resistance and rRNA genes; and an expanded level of susceptibility data with MIC test results.
Minimum inhibitory concentration (MIC) ranges for resistant, intermediate, and susceptible are based on criteria within the Clinical and Laboratory Standards Institute (CLSI) Performance Standards for Antimicrobial Susceptibility Testing, 26th Edition.
Predicted antimicrobial resistance gene sequence data are provided for informational purposes only and are based on open reading frames (ORFs) identified and annotated from contigs produced during next-generation sequencing (NGS). ATCC does not warrant that the entire predicted antimicrobial resistance gene is present within the sequence prepared for lot-specific reports. Likewise, the information provided merely indicates that some portion of the sequence (whole or in part) is present based on analytical base pair alignment with known gene sequences. |
| Medium |
ATCC® Medium 18: Trypticase Soy Agar/Broth
|
| Growth Conditions |
Temperature: 37°C
Atmosphere: Aerobic |
| Name of Depositor |
International Health Management Associates (IHMA), Inc. |
| Special Collection |
Global Priority Superbugs |
| Chain of Custody |
ATCC <-- International Health Management Associates (IHMA), Inc. |
| Patient Age |
83 |
| Patient Gender |
Male |
| References |
Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing, 26th Edition. Wayne, PA. M100S, 2016.
|
